Blood Damage Modeling

Overview

​In vitro testing of hemolysis and thrombosis is essential for the development of various blood-contacting devices. Computational fluid dynamics has also proven to be a useful complementary tool for understanding mechanical sources of damage, i.e. shear stress, exposure time, and recirculation, but lacks clear regulatory impact.

Benefits

These models will help medical device developers understand and optimize their devices to minimize the effects of blood damage during the product development stage and, potentially, assist in assessing safety.

Blood Damage Models Focus Areas

Blood Damage Models - Hemolysis

This work stream will feed into a subsequent effort to develop predictive computational models of hemolysis, helping medical device developers understand and reduce hemolysis during product development.
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Blood Damage Models - Thrombosis

This work stream will feed into a subsequent effort to develop predictive computational models of thrombosis, helping medical device developers understand and optimize thrombo-resistance during product development.
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Deliverable

To generate credible physical test data that can then be used to support the development and validation of computational models of blood damage.

Join us!

To learn more, please contact MDIC staff at CMS@mdic.org.

Computational Modeling and Simulation Program

Check out the Computational Modeling and Simulation overview to learn more about projects, initiatives, news, upcoming events.

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