March 30, 2019

This RFI is a request for technical information about available and possible approaches for creating a set of human cell lines that include all (or subsets of) the variants listed in ‘Priority Variant List.’ These variants are drawn from a larger list developed by the MDIC SRS working group and includes clinically actionable oncogene variants. The MDIC SRS working group is also interested to incorporate variants in tumor suppressor genes into a possible set of future reference samples.