Somatic Reference Sample Project Proposal

Project Proposal was released in April 2018 for the Somatic Reference Sample project. The ultimate goal of the effort is to develop properly consented, widely shareable reference samples that can be made available to the public, is scalable, and produced in order to enable efficient development and improve the accuracy, reliability and transparency of NGS-based oncology tests. These samples are intended to be quality checked and validated, and made available in varying forms (e.g., cells, DNA/RNA, FFPE), represent the majority of potential variations and allele fractions of interest (e.g., ploidy, fusions, large/small indels, CNVs, homopolymeric regions), and represent tumor/normal matched pairs.